Francis D. Pagani, MD, Ph.D. and Roberto Merlin, Ph.D.
Patients with advanced heart failure have limited options due to a limited donor heart supply. The most promising alternative to transplantation has been implantable left ventricular assist devices (LVAD). However, one of the major limitations with the current generation of LVAD is the need for a Continue Reading »
Cynthia Chestek, Ph.D., Paul Cederna, MD
Every day in the US, 507 people lose a limb; while, 1000 children per year are born with limb defects. The use of prosthetic devices may determine whether persons with amputations return to work. Advanced prosthetic limbs now provide motorized joints with fine controls and sensorization similar to normal Continue Reading »
Daniel Teitelbaum, MD and Jonathan Luntz, Ph.D.
In the US 20,000 patients suffer from short bowel syndrome. The decreased bowel length, results in insufficient nutrient absorption necessitating IV or parenteral nutrition (PN) as a mainstay of treatment. For many patients, PN is the only long term solution for this condition, and severely hampers both quality Continue Reading »
Cagri Besirli MD, Ph.D., Kevin Pipe, Ph.D.
The ability to deliver medication directly into the eye via intravitreal injection therapy (IVT) has transformed the treatment landscape of a number of previously blinding diseases, including macular degeneration and diabetic retinopathy. The success of these therapies in preventing blindness has resulted in a dramatic increase in the Continue Reading »
Timothy Cornell, MD and Katsuo Kurabayashi, Ph.D.
There are over 5 million intensive care unit admissions per year in the U.S. Approximately 4 million of these patients will experience some degree of immune dysfunction, the most severe of which is ‘cytokine release syndrome’ (CRS). Severe CRS results in rapid hemodynamic instability, and ultimately multisystem organ Continue Reading »
Paul Cederna, MD, Adeyiza Momoh, MD, Albert Shih, Ph.D., and Jeffrey Plott
Approximately 5.8 million reconstructive procedures were performed by board certified plastic surgeons in 2014. Free tissue transfers from one part of a patient’s body to another provide a means for reconstructive surgeons to repair and replace body parts, restoring appearance and in many Continue Reading »